GNS Healthcare Blog

GNS Healthcare Blog

GNS Healthcare Primary Blog

By December 31, 1969

Real World Evidence: How It's Changing the Way Drugs are Developed and Valued

In the summer of 1996, two new prescription drugs, containing fenfluramine and phentermine, hit the market promising an easy way to lose weight. Use of the products skyrocketed and by mid 1997, almost two million people were taking them¹.

Just over a year later, in September of 1997, both products were abruptly pulled off the market amid growing concerns that use of the drugs may cause serious heart problems. The FDA found evidence that nearly one-third of those taking the drugs might develop a rare form of heart valve damage that could weaken the heart. Three deaths were linked to the use of...

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